Related Experiment Video
Updated: Jun 7, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Effects of Fasting on Metabolic Hormones and Functions: A Narrative Review
Abstract:
The occurrence of the metabolic syndrome and its related diseases such as diabetes are steadily rising in our modern society. Modern food choices and the more sedentary lifestyles largely contribute to this shift in our society's health. Fasting has been practiced for religious purposes all over the world long time before science showed the benefits of it. The effects of fasting on glucose and fat metabolism are of great interest. Fasting triggers a cascade of changes in the hormonal, microbiome and enzymatic environments, leading to shifted glucose and fat metabolisms. Fasting-induced metabolic function changes are affected by several factors such as sex hormones, lipid-released hormones, growth hormone, insulin, and the gut microbiome, leading to lipolysis and the release of FFA into the bloodstream. The purpose of this review is to summarize the newest research results on the specific pathways fasting triggers to improve metabolic functions and understand the potential applications of fasting as prevention/treatment of several metabolic conditions.
More Related Videos
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
11:03Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes
Published on: September 9, 2021
Related Concept Videos
Metabolic States of the Body: Fasting and Starvation
Metabolic States of the Body: The Postabsorptive State
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Glucose Homeostasis: Regulation of Blood Glucose
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
Regulation of Metabolism
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...