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Capturing Chemotherapy and Radiotherapy Dose Among Breast Cancer Patients With the Utah All-Payer Claims Database
Alzina Koric1,2, Chun-Pin Esther Chang2,3, Shane Lloyd2,4
1Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
Cancer Medicine
|November 16, 2024
Summary
The Utah All-Payer Claims Database (APCD) accurately identifies breast cancer treatment agents but has moderate utility for capturing precise dosages. Combining APCD with other data sources enhances cancer treatment information completeness.
Area of Science:
- Health Informatics
- Cancer Research
- Data Validation
Background:
- The Utah statewide All-Payer Claims Database (APCD) is a valuable resource for health services research.
- Validating the accuracy of cancer treatment data within the APCD is crucial for its reliable use.
Purpose of the Study:
- To assess the validity of the Utah APCD for capturing breast cancer-specific treatments and dosages.
- To compare APCD data against gold-standard medical record abstractions.
Main Methods:
- A pilot study abstracted breast cancer treatments from medical records (gold standard) for patients diagnosed in 2013.
- Compared treatments identified in the APCD with abstracted data using sensitivity, specificity, and intraclass correlation coefficients (ICC).
Main Results:
- APCD demonstrated high sensitivity in identifying chemotherapy agents (e.g., 91% for carboplatin, 94.7% for biologic therapy).
- Chemotherapy dosage consistency between APCD and abstraction ranged from 63% to 76%.
- Radiotherapy regimen identification sensitivity was 66%, with an ICC of 54% for dosage.
Conclusions:
- The APCD is highly reliable for identifying specific cancer treatment agents like carboplatin, docetaxel, and trastuzumab.
- The APCD has moderate utility for capturing detailed treatment dosage information.
- Integrating multiple data sources, including the APCD, improves the completeness of cancer treatment data.
