Related Experiment Video
Updated: Jun 7, 2025
Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
Published on: March 1, 2024
Comparison of responders and nonresponders with knee osteoarthritis after transcranial direct current stimulation
Juyoung Park1, Heling Tong2, Yixin Kang2
1College of Nursing, The University of Arizona, Tucson, AZ, USA.
Aim:
The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.
Patients And Methods/Materials:
Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.
Results:
Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders (p < .001). Participants with higher BMI (p = .02) and weight (p = .005) were more likely to respond, while no significant sociodemographic differences were found.
Conclusions:
Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.
Clinical Trial Registration:
www.clinicaltrials.gov identifier is NCT04016272.
