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The Year in Cardiothoracic Transplant Anesthesia: Selected Highlights From 2022 Part II: Cardiac Transplantation
Elizabeth Ungerman1, Oriana C Hunter2, Arun L Jayaraman3
1Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, PA.
Journal of Cardiothoracic and Vascular Anesthesia
|November 17, 2024
Summary
Research in 2022 advanced heart transplantation by optimizing donor and recipient factors, refining surgical techniques, and exploring new frontiers like xenotransplantation. Key areas include recipient assessment, organ preservation, and managing postoperative complications for better patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Transplantation Medicine
- Immunology
Background:
- Heart transplantation is a critical treatment for end-stage heart failure.
- Continuous research is vital to improve patient selection, surgical outcomes, and long-term graft survival.
- The year 2022 saw significant advancements across the entire transplantation continuum.
Purpose of the Study:
- To summarize key research advancements in heart transplantation published in 2022.
- To provide an overview of progress in preoperative, intraoperative, and postoperative care.
- To highlight emerging trends and challenges in the field.
Main Methods:
- Review of peer-reviewed research published in 2022 focusing on heart transplantation.
- Categorization of research into preoperative, intraoperative, and postoperative phases.
- Inclusion of diverse recipient factors, donor strategies, surgical techniques, and post-transplant management.
Main Results:
- Preoperative research covered candidate assessment, donor optimization (including extended criteria donors and donation after circulatory death), and recipient factors (e.g., comorbidities, cannabis use, policy impacts).
- Intraoperative advancements included multidisciplinary team utilization, transfusion protocols, allograft preparation, and size matching.
- Postoperative research focused on tricuspid regurgitation, echocardiography, arrhythmia management, and xenotransplantation.
Conclusions:
- 2022 research has significantly refined heart transplantation protocols and addressed critical challenges.
- Ongoing research into recipient factors, organ utilization, and surgical innovation continues to improve outcomes.
- Emerging areas like xenotransplantation show future promise for addressing donor organ shortages.

