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Updated: Jun 7, 2025
Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
Published on: February 24, 2023
Tunnel sign in patients with melioidosis: a case series from South India
Nitin Gupta1, Sundeep Malla2, Tirlangi Praveen Kumar1
1Department of Infectious Diseases, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, India.
Introduction:
The tunnel sign (linear contrast enhancement along the corticospinal tract) can aid in the early diagnosis of neuromelioidosis, a potentially fatal condition requiring urgent diagnosis.
Methodology:
We retrospectively analyzed the hospital data of all patients with culture-confirmed melioidosis between 2018 and 2023 in a tertiary care hospital in South India. MRI scans of patients with neuromelioidosis were reviewed for the presence of the tunnel sign.
Results:
Of the 177 patients with melioidosis, 21 had possible neurological involvement. Seven had confirmed neuromelioidosis. Of the six patients with neuromelioidosis, where an MRI scan was available, a tunnel sign was noted in four.
Conclusion:
We report this study to create awareness amongst physicians to look for this sign in patients with suspected neuromelioidosis.
