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A Case of Resectable Single-Nodule Intrahepatic Bile Duct Adenoma
Hiroshi Okano1, Hiroki Asakawa2,3, Katsumi Mukai1
1Gastroenterology, Suzuka General Hospital, Suzuka, JPN.
Cureus
|November 18, 2024
Summary
A rare bile duct adenoma (BDA) was incidentally found in a 70-year-old man. Surgical removal confirmed the benign tumor, with no recurrence after five years, highlighting the importance of monitoring.
Area of Science:
- Hepatobiliary Medicine
- Surgical Pathology
- Diagnostic Imaging
Background:
- Bile duct adenomas (BDAs) are rare benign tumors of the liver.
- Preoperative diagnosis can be challenging, often requiring surgical resection for definitive characterization.
- BDAs have a potential risk of malignant transformation into cholangiocarcinoma.
Observation:
- A 70-year-old male presented with an incidentally discovered hepatic mass lesion.
- Imaging studies (CT, MRI, hepatic angiography) showed consistent contrast enhancement.
- The lesion demonstrated slight enlargement over two months, prompting surgical intervention.
Findings:
- Pathological examination confirmed the resected lesion as a bile duct adenoma.
- Histological features included dense proliferative small gland cavities.
- Immunohistochemistry revealed positive CK7 and negative p53 staining.
Implications:
- Surgical resection is a viable option for managing bile duct adenomas.
- The patient achieved a favorable outcome with no recurrence five years post-hepatectomy.
- Close monitoring or surgical resection of suspected BDAs is crucial due to malignant potential.
