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Atherogenic indices in preeclamptic and eclamptic patients in North-Central Nigeria
Zainab Ajoke Abdulkadir1, Munirdeen Aderemi Ijaiya2, Idowu O Adebara3
1General Hospital Ilorin, Ilorin, Nigeria.
Abstract:
Microvascular, placental, haematological and lipid studies suggest striking similarities between preeclampsia/eclampsia and atherosclerosis.
Objective:
To determine the lipid profile and atherogenic indices in preeclamptic/eclamptic patients and compare with normal pregnant women.
Methodology:
Comparative cross-sectional study conducted in North Central Nigeria. The study population was preeclamptic/eclamptic patients and normal pregnant women. A total of 192 women, comprising 96 pregnant women with preeclampsia/eclampsia and an equal number of normotensive controls were recruited consecutively by purposive sampling. Lipid profiles were estimated and atherogenic indices were calculated.
Result:
Coronary heart disease risk ratio (CRR) and atherogenic index of plasma (AIP) showed significantly increased atherogenic potentials in subjects compared to controls. Mean ± SD CRR of subjects was 0.28 ± 0.17, Mean ± SD CRR of controls was 0.44 ± 0.24 (p = 0.001); Mean ± SD AIP of subjects was 0.32 ± 0.42 and mean ± SD AIP of controls was 0.16 ± 0.26 (p = 0.003).
Conclusion:
Atherogenic indices show increased atherogenic potentials in preeclamptic/eclamptics.
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