Related Experiment Video
Updated: Jun 7, 2025

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST
Published on: April 23, 2015
Of Mice and Mates: Automated Classification and Modelling of Mouse Behaviour in Groups Using a Single Model Across
Michael P J Camilleri1, Rasneer S Bains2, Christopher K I Williams1
1School of Informatics, University of Edinburgh, Edinburgh, UK.
Abstract:
Behavioural experiments often happen in specialised arenas, but this may confound the analysis. To address this issue, we provide tools to study mice in the home-cage environment, equipping biologists with the possibility to capture the temporal aspect of the individual's behaviour and model the interaction and interdependence between cage-mates with minimal human intervention. Our main contribution is the novel Global Behaviour Model (GBM) which summarises the joint behaviour of groups of mice across cages, using a permutation matrix to match the mouse identities in each cage to the model. In support of the above, we also (a) developed the Activity Labelling Module (ALM) to automatically classify mouse behaviour from video, and (b) released two datasets, ABODe for training behaviour classifiers and IMADGE for modelling behaviour.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s11263-024-02118-3.

