Sacroiliac joint dysfunction: anatomy, pathophysiology, differential diagnosis, and treatment approaches

The sacroiliac joints (SIJ) play a pivotal role in pelvic stability and load transmission. SIJ-related disorders can pose a diagnostic challenge because of complex anatomy, non-specific imaging findings, and overlapping symptomatology with other lower back conditions. Broadly, SIJ pathology can be divided into the following categories: infectious, inflammatory, degenerative, mechanical, traumatic, and neoplastic. On the spectrum of mechanical disorders is the entity of SIJ dysfunction, defined as pain localized to the SIJ due to non-inflammatory causes. This paper aims to enhance the understanding of SIJ dysfunction by exploring SIJ anatomy, pathophysiology, and differential diagnosis for SIJ pain. Etiologies, associations, and diagnostic physical examination maneuvers for SIJ dysfunction are reviewed. We will discuss the role of diagnostic imaging in SIJ dysfunction and propose imaging findings which may indicate the diagnosis. Finally, we will discuss therapeutic strategies to treat SIJ dysfunction. By delving into the complexities of SIJ anatomy and pathophysiology, this paper provides valuable discernment for the diagnosis and management of SIJ-related disorders.