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Area of Science:

  • Artificial Intelligence in Medicine
  • Natural Language Processing
  • Health Informatics

Background:

  • Transformer-based language models show potential in healthcare for clinical decision support, patient interaction, and disease prediction.
  • Implementation in clinical settings is limited due to a lack of comprehensive reviews, hindering systematic understanding.
  • Difficulties in effective use lead to inefficient research and slow integration into clinical workflows.

Purpose of the Study:

  • To address the gap in understanding by examining studies on medical transformer-based language models.
  • To categorize these models into six key healthcare tasks: dialogue generation, question answering, summarization, text classification, sentiment analysis, and named entity recognition.

Main Methods:

  • A scoping review was conducted following the Cochrane protocol.
  • A comprehensive literature search spanned January 2017 to September 2024 across major databases.
  • Studies involving transformer-derived models in medical tasks were included and categorized.

Main Results:

  • Key findings highlight both advancements and critical challenges in applying transformer models to healthcare.
  • Models like MedPIR (dialogue generation) show promise but raise privacy/ethical concerns.
  • Question-answering models (e.g., BioBERT) improve accuracy but struggle with medical terminology complexity; summarization models (e.g., BioBERTSum) need better long-sequence handling.

Conclusions:

  • This review consolidates the role of transformer models in healthcare and guides future research.
  • Addressing identified challenges can enable significant improvements in healthcare delivery and patient outcomes.
  • Valuable insights are provided for future research and practical applications in medical informatics.