Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

FeNO as a Treatable Trait in Chronic Cough: Insights from the PROCOUGH Study.

Lung·2026

Same author

Asthma diagnosis in adults and children: challenges, future directions, and a call to action.

The Lancet. Respiratory medicine·2026

Same author

Use of oscillatory positive expiratory pressure (OPEP) devices to augment sputum clearance in COPD: An updated systematic review and meta-analysis.

Chronic respiratory disease·2026

Same author

Age-Dependent Role of Cough Hypersensitivity in Transition to Refractory Chronic Cough.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026

Same author

Clinically Meaningful Differences for Cough-Specific Visual Analogue Scale in Chronic Cough: A Real-World Study.

Lung·2026

Same author

Reduced cough severity and improved confidence in self-management following completion of a Virtual Physiotherapy Group Intervention for Chronic Cough: ViP-Cough.

ERJ open research·2026

Search research articles

Related Experiment Video

Updated: Jun 7, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

The Clinical Approach to Chronic Cough.

Imran Satia¹, Wafa Hassan², Lorcan McGarvey³

¹Department of Medicine, McMaster University, Hamilton, ON, Canada; Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamilton, ON, Canada.

The Journal of Allergy and Clinical Immunology. in Practice

|November 18, 2024

Summary

Chronic cough affects 10% of people, impacting quality of life. New treatments target cough hypersensitivity, offering hope for refractory chronic cough (RCC) management.

Keywords:

Antitussive Chronic cough Neuronal dysfunction Vagus nerve

More Related Videos

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

Related Experiment Videos

Last Updated: Jun 7, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

Area of Science:

Respiratory Medicine
Neurology
Pharmacology

Background:

Chronic cough affects 10% of the population, significantly impairing quality of life.
Refractory chronic cough (RCC) presents a major clinical challenge.
Cough hypersensitivity syndrome, a neuropathic mechanism, is increasingly recognized in RCC.

Purpose of the Study:

To review current investigations into the pathophysiology of chronic cough and RCC.
To summarize emerging management strategies for chronic cough and RCC.
To highlight the "treatable trait" approach and novel therapeutic targets.

Main Methods:

Review of current scientific literature on chronic cough and RCC.
Analysis of emerging treatment modalities, including neuromodulators and receptor antagonists.
Discussion of the "treatable trait" approach in managing chronic cough.

Main Results:

The "treatable trait" approach is gaining traction for managing chronic cough.
Neuropathic mechanisms and cough hypersensitivity are key in RCC.
New treatments, including P2X3 receptor antagonists, show promise but patient responses vary.

Conclusions:

Understanding cough hypersensitivity is crucial for managing RCC.
Targeting neuronal pathways offers new therapeutic avenues.
Further research is needed to optimize treatment strategies for RCC due to variable patient responses.