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Enantioselective Membranes for Pharmaceutical Applications: A Comprehensive Review
Monti Gogoi1, Rajiv Goswami1, Akhil Ranjan Borah1,2
1Chemical Engineering Group and Centre for Petroleum Research, CSIR-North East Institute of Science and Technology, Jorhat, Assam, India.
Biomedical Chromatography : BMC
|November 18, 2024
Summary
Enantioselective membranes offer efficient chiral separation for pharmaceuticals and biological applications. This review covers their fabrication, properties, and future potential in advanced separation technologies.
Area of Science:
- Membrane Science and Separation Technology
- Chiral Chemistry
- Biotechnology
Background:
- Chiral separation is critical in pharmaceutical and biological fields.
- Enantioselective membranes provide a highly selective and efficient platform for separating chiral molecules.
- Their unique properties like large surface area and tunable pore size enhance separation efficiency.
Purpose of the Study:
- To provide a comprehensive review of recent advancements in enantioselective membranes for chiral separation.
- To discuss various fabrication methods, functionalization strategies, and characterization techniques.
- To highlight applications, challenges, and future directions in the field.
Main Methods:
- Review of literature on enantioselective membrane fabrication techniques.
- Analysis of functionalization approaches for enhanced chiral recognition.
- Examination of characterization methods for membrane performance evaluation.
- Discussion of case studies in drug delivery, biomolecule separation, and pharmaceutical analysis.
Main Results:
- Enantioselective membranes demonstrate significant potential for efficient enantiomer separation.
- Various fabrication and functionalization methods allow for tunable selectivity and permeability.
- Successful applications in drug delivery and pharmaceutical analysis have been reported.
Conclusions:
- Enantioselective membranes are a key technology for advanced chiral separations.
- Continued research into fabrication, functionalization, and application is crucial.
- Addressing current challenges will unlock future potential in pharmaceutical and biological separations.
Keywords:
biomedical researchchiral separationefficiencyenantioselective membranespharmaceutical analysisMore Related Videos
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