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Related Experiment Video

Updated: May 6, 2026

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Pain in Tourette Syndrome: A Comprehensive Review.

Bryan Green1, Allison Waters2, Joohi Jimenez-Shahed3

  • 1Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Journal of Child and Adolescent Psychopharmacology
|November 19, 2024
PubMed
Summary
This summary is machine-generated.

Pain is common in Tourette syndrome (TS), affecting up to 60% of patients and impacting quality of life. Further research is needed to understand pain mechanisms and develop effective treatments for this symptom in TS.

Keywords:
Tourette syndromeinteroceptionpainpain managementsensorysensory gatingtic disorder

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Area of Science:

  • Neurology
  • Pain Medicine
  • Psychiatry

Background:

  • Tourette syndrome (TS) is frequently associated with pain, yet this aspect remains under-investigated.
  • Existing survey data indicate a high prevalence of pain among individuals with TS.
  • Systematic investigation into pain features in TS is lacking.

Purpose of the Study:

  • To review the current understanding of pain in Tourette syndrome.
  • To assess the impact of pain on the quality of life for individuals with TS.
  • To identify future research priorities for pain in TS.

Main Methods:

  • Comprehensive literature search of PubMed and Scopus databases.
  • Inclusion of peer-reviewed primary research and review articles.
  • Use of search terms: Tourette syndrome, tic disorder, pain, pain management, sensory, and sensory gating.

Main Results:

  • Pain affects 47%-60% of individuals with TS, exceeding general population prevalence.
  • Pain in TS can be linked to tic phenomenology, sensory processing, or other causes.
  • Proposed classification for TS-related pain includes tic-related, suppression-related, urge-related, and associated primary pain syndromes.

Conclusions:

  • Tourette syndrome can involve chronic pain syndromes that significantly impair quality of life.
  • Current TS assessment tools often lack adequate pain evaluation.
  • Further research is crucial to elucidate pain mechanisms, develop assessment tools, and explore therapeutic options for pain in TS.