Clinical and Histopathological Perspectives of Pilomatrixoma: A Case Report

Pilomatrixoma is a rare, benign tumor arising from hair follicle matrix cells, commonly seen in children and young adults. This case report discusses an 8-year-old male with a progressively enlarging posterior neck swelling over three months. Clinical examination revealed a mobile, subcutaneous mass. Fine-needle aspiration cytology (FNAC) suggested an adnexal tumor, characterized by cohesive clusters of basaloid cells, nucleated and anucleated squamous cells, and ghost cells. The patient underwent surgical excision of the mass, and histopathological examination confirmed a diagnosis of pilomatrixoma. Postoperative recovery was uneventful, with no signs of recurrence at the three-month follow-up. This case highlights the importance of combining clinical, cytological, and histopathological findings to accurately diagnose and manage pilomatrixoma, emphasizing the role of complete surgical excision in achieving favourable outcomes. The report adds valuable insights to the literature, aiding clinicians in recognizing and differentiating this rare tumour in paediatric patients.