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Perplexing paradoxical reactions: navigating the complexity of protracted tuberculosis meningitis-a case report

Megan S Gooding1, Dima A Hammoud2, Brian Epling3

  • 1Clinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, MD, United States.

Frontiers in Immunology
|November 19, 2024
PubMed
Summary

Paradoxical reactions (PRs) complicate tuberculous meningitis (TBM) treatment, often requiring drug dose adjustments and intensified regimens. Biomarker analysis reveals elevated inflammatory markers in PRs, aiding future diagnostics and treatment strategies for TBM.

Keywords:
case seriesimmunocompetentparadoxical reactiontherapeutic drug monitoringtuberculous meningitis

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