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Acute immuno-allergic tubulo-interstitial nephritis due to amoxicillin confirmed by rechallenge
Laure Mondo1, Amira Bendjama1, Maxime Taghavi2
1Service de médecine interne, Hôpital universitaire Brugmann, Université libre de Bruxelles, Bruxelles, Belgique
Abstract:
Acute kidney injury is a common drug adverse reaction and may concerned antibiotics. We report a case of an acute renal failure due to amoxicillin occurring twice in the same patient. Two mechanisms have been described for amoxicillin, with an immuno-allergic origin observed in our case. The diagnosis, supported by kidney biopsy, was confirmed by rechallenge with this patient.

