Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electrical stimulation of bone growth with direct current.

C L Lagey, J M Roelofs, L W Janssen

    Clinical Orthopaedics and Related Research
    |March 1, 1986
    PubMed
    Summary

    Electrical stimulation did not enhance bone growth with a cortex-depolarizing field. However, bone growth was significantly stimulated by an intramedullary cathode with a distant anode, indicating potential for osteogenesis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Corrigendum to "The effect of continuous or intermittent calorie-restricted diet on body composition and resting energy expenditure in patients with type 2 diabetes"[Clin Nutr ESPEN 72 (2026) 102940].

    Clinical nutrition ESPEN·2026
    Same author

    Reply - Letter to the editor "Comment on "The effect of continuous or intermittent calorie-restricted diet on body composition and resting energy expenditure in patients with type 2 diabetes"".

    Clinical nutrition ESPEN·2026
    Same author

    The effect of continuous or intermittent calorie-restricted diet on body composition and resting energy expenditure in patients with type 2 diabetes.

    Clinical nutrition ESPEN·2026
    Same author

    Body composition is associated with tacrolimus pharmacokinetics in kidney transplant recipients.

    European journal of clinical pharmacology·2022
    Same author

    Localization of(99m)Tc in bone by means of autoradiography.

    Biological trace element research·2013
    Same author

    Use of laser microprobe mass analysis (LAMMA) for localizing multiple elements in soft and hard tissues.

    Biological trace element research·2013

    Area of Science:

    • Biomedical Engineering
    • Orthopedic Research
    • Bone Physiology

    Background:

    • Electrical stimulation is explored for its potential to influence bone growth and healing.
    • Understanding the optimal parameters for electrical stimulation is crucial for therapeutic applications in orthopedics.

    Purpose of the Study:

    • To investigate the effects of different electrical field configurations on osteogenesis in rabbit femora.
    • To determine if specific orientations of electric fields can stimulate bone growth.

    Main Methods:

    • Rabbit femora were subjected to electrical stimulation using intramedullary and external electrodes with a direct current of 20 microA for six weeks.
    • Two configurations were tested: transcortical electric field and an intramedullary electrode with an abdominal wall counter electrode.

    Related Experiment Videos

  • Bone growth was assessed using optical densitometry of roentgenograms and histomorphometry.

    • Main Results:

    • A cortex-depolarizing electric field did not stimulate bone growth.
    • Significant bone growth stimulation was observed when an intramedullary cathode was used with a distant anode.
    • No significant difference was noted in control femora with dummy electrodes.

    Conclusions:

    • The orientation and placement of electrodes are critical factors in electrical stimulation of bone growth.
    • Anodal-distant cathode configuration shows promise for stimulating osteogenesis.
    • Further research is warranted to optimize parameters for clinical applications.