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Related Experiment Videos

Selenium metabolism and function.

R J Shamberger

    Clinical Physiology and Biochemistry
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Selenium exhibits a dual effect, acting as an essential trace element for growth at low doses but becoming toxic at higher concentrations for humans and animals. Its role in glutathione peroxidase and analytical properties are also discussed.

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    Area of Science:

    • Biochemistry
    • Environmental Science
    • Toxicology

    Background:

    • Selenium is an element with a known dual biological effect.
    • It is essential for human and animal growth at trace concentrations.
    • However, elevated selenium levels can lead to toxicity.

    Purpose of the Study:

    • To outline the bimodal effects of selenium.
    • To describe the biochemical role of selenium.
    • To detail the analytical properties of selenium.

    Main Methods:

    • Literature review on selenium's biological and chemical properties.
    • Analysis of selenium's role in glutathione peroxidase.
    • Summary of analytical methods for selenium detection.

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    Main Results:

    • Selenium is essential at low concentrations and toxic at high concentrations.
    • Selenium is a key component of the antioxidant enzyme glutathione peroxidase.
    • Various analytical techniques can be used to determine selenium levels.

    Conclusions:

    • Selenium's concentration-dependent effects are critical for biological systems.
    • Understanding selenium's biochemistry and analytical properties is vital for managing its impact.
    • Further research may elucidate more on selenium's complex biological functions.