Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

67
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
67
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

131
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
131

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal GGT Trajectories Identify Prognostic Phenotypes in Paediatric Primary Sclerosing Cholangitis.

JHEP reports : innovation in hepatology·2026
Same author

The predictive value of intestinal ultrasound for treatment response in inflammatory bowel disease: a systematic review and pooled data analysis.

Journal of Crohn's & colitis·2026
Same author

Reply.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie·2026
Same author

Update in clinical science: MASLD in children and adolescents.

Journal of hepatology·2026
Same author

Children's experience of screening and evaluation for MASLD in overweight and obesity.

Obesity research & clinical practice·2025
Same journal

Ultrasound-guided midline catheters in the neonatal intensive care unit: a single-center pilot study.

European journal of pediatrics·2026
Same journal

Gastrointestinal pathogens in paediatric patients with diarrhoea during the COVID-19 pandemic in Spain: a multicentre molecular-based prospective study.

European journal of pediatrics·2026
Same journal

Low serum immunoglobulin levels in pediatric atopic dermatitis: association with disease severity and exploratory scores.

European journal of pediatrics·2026
Same journal

Safely developing respiratory care during emergency neonatal transport through systematic collection and analysis of detailed ventilator data.

European journal of pediatrics·2026
Same journal

Validity and reliability of the Turkish version of the Physical Activity Parenting Questionnaire for Children.

European journal of pediatrics·2026
Same journal

Correction to: A novel oxygenation distension index (ODI): a driving pressure-based metric compared with the oxygenation index in pediatric PARDS.

European journal of pediatrics·2026
See all related articles

Related Experiment Video

Updated: Jun 7, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

49.7K

Pediatric MASLD: current understanding and practical approach.

Anne-Sophie R Stroes1, Miriam Vos2, Marc A Benninga1

  • 1Department of Pediatric Gastroenterology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

European Journal of Pediatrics
|November 19, 2024
PubMed
Summary
This summary is machine-generated.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing concern in children, linked to obesity. New criteria and emerging treatments highlight the importance of early identification and management of this liver condition.

Keywords:
ChildrenMASHMASLDObesity

More Related Videos

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

786
Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

8.4K

Related Experiment Videos

Last Updated: Jun 7, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

49.7K
Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

786
Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

8.4K

Area of Science:

  • Pediatric Gastroenterology and Hepatology
  • Metabolic Disorders
  • Public Health

Background:

  • Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading chronic liver disease in children globally, driven by increasing obesity rates.
  • MASLD is associated with significant risks, including progressive liver damage, type 2 diabetes mellitus, and cardiovascular disease.
  • Current challenges include underdiagnosis due to low awareness and the absence of straightforward diagnostic criteria.

Purpose of the Study:

  • To review the epidemiology and risk factors of pediatric MASLD.
  • To provide an evidence-based approach for screening, diagnosis, and treatment of MASLD in children.
  • To highlight recent advancements in diagnostic criteria and emerging therapeutic options.

Main Methods:

  • Literature review of current evidence and expert opinion on pediatric MASLD.
  • Analysis of epidemiological data and risk factors.
  • Synthesis of updated diagnostic guidelines and treatment strategies.

Main Results:

  • MASLD is strongly associated with childhood obesity, overweight, and insulin resistance.
  • New diagnostic criteria simplify the identification of MASLD, shifting it from a diagnosis of exclusion to a positive diagnosis.
  • Emerging effective treatments for adults suggest potential future therapies for children.

Conclusions:

  • Early identification of pediatric MASLD is crucial, especially with new diagnostic tools and potential treatments on the horizon.
  • A proactive approach to screening, diagnosis, and management is needed to address the rising prevalence of MASLD.
  • Further research is warranted to optimize treatment strategies for children with MASLD.