Related Experiment Video
Updated: Jun 7, 2025
In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
Multimodal Imaging in Unilateral Acute Idiopathic Maculopathy with Staphylococcus aureus Infection
Padmamalini Mahendradas1, Aditya Patil1, Rahul Patil2
1Department of Uveitis and Ocular Immunology Services, Narayana Nethralaya, Bangalore, India.
Purpose:
To report the multimodal imaging findings in the case of unilateral acute idiopathic maculopathy (UAIM) associated with Staphylococcus aureus infection in a young girl with good clinical outcome.
Methods:
Rare case report with multimodal imaging including fundus photography, optical coherence tomography (OCT), autofluorescence, multicolor imaging, OCT angiography, fluorescein angiography (FA), and polarization sensitive OCT (PS-OCT).
Results:
A 13-year-old girl presented with blurring of vision in the left eye (OS). Fundus examination revealed yellowish subretinal deposits at the fovea in OS with findings resembling UAIM on ophthalmoscopy, OCT, and FA. We noted the OCT angiography and PS-OCT findings in this case. Blood culture revealed the growth of Staphylococcus aureus. Autoimmune work-up was negative. Patient was treated with appropriate systemic antibiotics. At 8 weeks follow-up, there was resolution of the lesion clinically and on OCT, with residual derangement of the retinal pigment epithelium.
Conclusion:
Our patient had UAIM presumed to have been triggered by systemic bacterial infection. The patient made an uneventful recovery following antimicrobial therapy. Multimodal imaging demonstrates the affection of the outer retinal layers and retinal pigment epithelium in this case.
