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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Rh Blood Group01:19

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Red Blood Cell Transfusion Practices: College of American Pathologists Q-Probes Studies of Red Blood Cell Utilization

Paul F Lindholm1, Rasleen K Saluja2, Thomas Long3

  • 1From the Department of Pathology, Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois (Lindholm).

Archives of Pathology & Laboratory Medicine
|November 19, 2024
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Summary
This summary is machine-generated.

Improving transfusion safety involves using lower hemoglobin thresholds and single-unit red blood cell (RBC) transfusions. Compliance with guidelines and single-unit practices reduce transfusions, leading to better patient outcomes.

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Area of Science:

  • Transfusion Medicine
  • Patient Blood Management

Background:

  • Transfusion safety can be enhanced by optimizing hemoglobin thresholds and adopting single-unit transfusion practices.
  • Compliance with transfusion guidelines is crucial for reducing unnecessary transfusions and improving patient outcomes.

Purpose of the Study:

  • To evaluate demographic and practice characteristics associated with lower hemoglobin thresholds and single red blood cell (RBC) unit transfusion practices.

Main Methods:

  • Utilized the College of American Pathologists (CAP) Q-Probes format using data from 2020 and 2017 surveys.
  • Analyzed transfusion review rates, compliance with institutional guidelines, and pre/post-transfusion hemoglobin values.

Main Results:

  • Institutions with high compliance, formal single-unit policies, and updated guidelines showed lower hemoglobin thresholds.
  • Single-unit transfusion use was higher in hospitals with patient blood management programs and in specific services like hematology/oncology and intensive care.
  • Favorable downward trends in hemoglobin thresholds and pre/post-transfusion hemoglobin values were observed between 2017 and 2020.

Conclusions:

  • Implementing single-unit transfusions and lower pretransfusion hemoglobin thresholds are key strategies for improving transfusion practices.
  • Opportunities exist to further reduce transfusion thresholds and increase single-unit transfusions, particularly in surgical and obstetrics services.