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Related Experiment Videos

Familial lichen planus.

A N Lin, H Srolovitz, R C Billick

    Cutis
    |February 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Familial lichen planus, a rare skin condition, occurred simultaneously in a mother and daughter. This suggests a genetic predisposition rather than an infectious cause for this rare dermatosis.

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    Area of Science:

    • Dermatology
    • Genetics
    • Epidemiology

    Background:

    • Lichen planus is an inflammatory condition affecting skin and mucous membranes.
    • Familial occurrences of lichen planus are rare, prompting investigation into potential causes.

    Observation:

    • Simultaneous generalized lichen planus was observed in a mother and her daughter.
    • Both patients responded positively to topical corticosteroid and salicylic acid treatment.

    Findings:

    • A review of 81 familial lichen planus cases revealed that 89% occurred in blood relatives.
    • The onset interval between familial cases varied significantly, from weeks to decades.

    Implications:

    • The findings support the hypothesis that genetic predisposition plays a role in familial lichen planus.
    • Further research into the genetic factors underlying lichen planus is warranted.