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Updated: Jul 18, 2026

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
Published on: July 25, 2015
Multimodality high-frequency ultrasound in the evaluation of cervical malignant lymphoma before biopsy
Hongyan Deng1, Kunpeng Cao1, Xinhua Ye1
1Department of Ultrasound, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Objective:
To investigate the application value of multimodality ultrasound in the evaluation of lymphoma.
Methods:
The regression models were performed to determine whether there were differences in differentiating lymphoma from benign lymph nodes. Receiver operator curves were drawn to evaluate the diagnostic performance of three ultrasound modalities.
Results:
Multivariate analysis showed statistically significant differences in the long to short axes ratio, visibility of the hilum, Adler grade of blood flow, cortical echo, maximum elasticity, elastic color pattern, enhancement distribution, and Area. The combination of three modalities achieved a sensitivity of 95.6%, specificity of 87.5%, accuracy of 93.5%, positive predicted value of 97.0%, and negative predicted value of 82.4%.
Conclusion:
Multimodal ultrasound can provide valuable differential diagnosis and improve the diagnostic performance.

