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Bronchoalveolar Lavage BAL for Research; Obtaining Adequate Sample Yield
Published on: March 24, 2014
Whole Lung Lavage in Autoimmune Pulmonary Alveolar Proteinosis: Unique Challenges in a Resource-Limited Setting
Ashesh Dhungana1, Buddhi Sagar Lamichhane1, Prajowl Shrestha1
1Department of Medicine - Chest Unit, Bir Hospital National Academy of Medical Sciences Kathmandu Nepal.
Abstract:
Autoimmune pulmonary alveolar proteinosis (PAP) is characterized by antibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF), alveolar macrophage dysfunction, and surfactant accumulation. Whole lung lavage (WLL) is the treatment of choice in patients with PAP and severe hypoxemia. In resource-limited settings, WLL can be performed in the intubated, anesthetized patient who is being one lung ventilated using a Y-type bladder irrigation catheter for saline instillation and drainage.
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