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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Bacterial Meningitis I: Introduction01:22

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Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
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Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

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Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
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Encephalitis l: Introduction01:19

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
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Brain Abscess l: Introduction01:26

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
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Related Experiment Video

Updated: May 6, 2026

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Anthrax meningoencephalitis: A case report.

Longshan Zhou1, Kun Liu1, Xiaoqian Yang2

  • 1Department of Neurosurgery, The Second People's Hospital of Liaocheng, Linqing, Shandong 252600, P.R. China.

Experimental and Therapeutic Medicine
|November 20, 2024
PubMed
Summary

A patient recovered from anthrax meningoencephalitis after diagnosis via cerebrospinal fluid testing. This case highlights the need for improved public awareness and occupational protection against Bacillus anthracis, especially for livestock handlers.

Keywords:
anthraxdetectionepidemiologymeningitis

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Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Microbiology

Background:

  • Anthrax meningoencephalitis is a rare but severe complication of Bacillus anthracis infection.
  • Cerebrospinal fluid rhinorrhea following head injury can create a pathway for retrograde bacterial infection.

Observation:

  • A patient presented with symptoms of bacterial encephalitis, including low cerebrospinal fluid sugar and high protein levels, after experiencing cerebrospinal fluid rhinorrhea.
  • Bacillus anthracis was detected in the patient's cerebrospinal fluid and blood, confirming anthrax meningoencephalitis.
  • Infection was traced to a butcher shop where the patient had purchased meat, with Bacillus anthracis found on a chopping board.

Findings:

  • The patient's anthrax meningoencephalitis was successfully treated, leading to recovery.
  • The case demonstrates a link between contaminated meat, cerebrospinal fluid rhinorrhea, and the development of anthrax meningoencephalitis.

Implications:

  • Strengthening medical personnel training for early detection, diagnosis, and treatment of anthrax is crucial.
  • Public education on anthrax awareness and prevention, particularly for those in livestock-related occupations, is urgently needed.
  • Enhanced occupational protection measures are essential for individuals involved in livestock breeding, slaughtering, and processing to prevent Bacillus anthracis transmission.