Related Experiment Video
Updated: Jul 12, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Debulking of a Sarcomatoid Renal Cell Carcinoma: An Unusual Clinical Presentation
Alexis Garza1, Maria V Rodriguez1, David Alonzo1
1Department of Urology, Doctor's Hospital at Renaissance Health, Edinburg, USA.
Abstract:
Sarcomatoid renal cell carcinoma (sRCC) is a form of renal cancer known for its aggressiveness and poor prognosis. This report presents the case of a 65-year-old male with an unusual presentation of sRCC. The patient presented with worsening kidney function, flank pain, hematuria, fatigue, and weight loss. Imaging revealed a large, heterogeneous renal mass with evidence of invasion into surrounding structures and lymph nodes. The patient underwent a radical nephrectomy, with the removal of affected structures en bloc, followed by radiation and adjunctive chemotherapy with pembrolizumab. This report discusses challenges in diagnosing sRCC, treatment options, and emerging therapies such as checkpoint inhibitors.
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