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Study on the correlation between abdominal infection and psychological stress in children based on nucleic acid
Gui-Bo Wang1, Xue-Feng Zhang2, Bing Liang2
1Department of Pediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China. heibaizhubobo@163.com.
Insights
Nucleic acid testing aids in diagnosing pediatric abdominal infections. The study also highlights the link between children's psychological stress and their mental health outcomes.
Area of Science:
- Pediatric infectious diseases
- Molecular diagnostics
- Child psychology
Background:
- Diagnosing and treating abdominal infections in children presents significant challenges.
- Nucleic acid detection offers a rapid and accurate diagnostic approach, crucial for effective management.
Purpose of the Study:
- To evaluate the utility of nucleic acid detection in diagnosing and treating pediatric abdominal infections.
- To explore the correlation between psychological stress and the condition in affected children.
Main Methods:
- Fifty pediatric patients with abdominal infections were analyzed.
- Pathogen identification involved culture, drug susceptibility testing, and broad-spectrum bacterial nucleic acid testing.
- Psychological assessments utilized the Coping with a Disease (CODI) scale.
Main Results:
- Specific antibiotic regimens (cefazoxime, piperacillin/tazobactam, metronidazole/ornidazole) showed 100% effectiveness for appendicitis based on susceptibility.
- Psychological evaluations indicated a positive correlation between pressure levels and anxiety/depressive disorders.
- Coping strategies like acceptance and distancing were linked to reduced anxiety and depression, while negative emotional responses exacerbated them.
Conclusions:
- Nucleic acid testing is valuable for diagnosing pediatric abdominal infections.
- The study underscores the importance of addressing children's mental health in conjunction with physical treatment.
Background:
Diagnosing and treating abdominal infection in children remains a challenge. Nucleic acid detection, as a rapid and accurate diagnosis tool, has great significance in this field.
Aim:
To investigate the diagnosis and treatment of abdominal infection by nucleic acid detection and its possible correlation with psychological stress in children.
Methods:
A total of 50 pediatric patients diagnosed with abdominal infections between September 2020 and July 2021 were included in this study. Intra-abdominal pus samples were collected for pathogen culture, drug susceptibility testing, and broad-spectrum bacterial nucleic acid testing. Psychological stress, anxiety, depression, and coping styles were assessed using the coping with a disease (CODI) scale.
Results:
Based on susceptibility testing, a regimen of cefazoxime, piperacillin/tazobactam, and metronidazole or ornidazole achieved 100% effectiveness in treating appendicitis. Psychological assessments revealed a positive correlation between pressure level and both anxiety (r = 0.324, P = 0.001) and depressive disorders (r = 0.325, P < 0.001). Acceptance and distancing as coping strategies were negatively correlated with anxiety and depression, while negative emotional responses were strongly associated with increased anxiety (r = 0.574, P < 0.001) and depression (r = 0.511, P = 0.001). Coping strategies such as illusion and escape showed no significant correlation with emotional outcomes.
Conclusion:
Nucleic acid testing helps in the diagnosis of abdominal infections in children, and also focuses on children's mental health.
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