Wernicke's Encephalopathy (WE) Associated with Hyperemesis Gravidarum (HG) Presenting with Psychiatric Morbidity:

Sandeep Grover1, Sanjana Kathiravan1, Akshyee Kale1

  • 1Dept. of Psychiatry, Post Graduate Institute of Medical Education & Research, Chandigarh, India.

Hyperemesis gravidarum (HG) can rarely cause Wernicke's encephalopathy (WE), with potentially severe neurological and psychiatric consequences. We describe two pregnant women who developed WE following prolonged vomiting, presenting with severe depression with catatonia and bipolar depression, respectively. These cases highlight the importance of early recognition of thiamine deficiency and prompt supplementation in HG.

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