Related Experiment Video
Updated: Jun 7, 2025
Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
Published on: July 14, 2023
Early wound healing in guided bone regeneration procedures using sodium hyaluronate and a pool of amino acids: a
Daniele Cardaropoli1,2, Lorenzo Tamagnone3, Luigi Laino4
1ProEd Institute for Professional Education in Dentistry, Turin, Italy - d.cardaropoli@proed.it.
Background:
Soft tissue healing is of paramount importance when guided bone regeneration techniques are used, as early exposure of the membrane could affect the results.
Methods:
In this randomized clinical trial, enrolling 20 patients, a gel rich in hyaluronic acid and amino acids was used to promote wound healing after a ridge augmentation procedure. The Early Wound Healing Index - EHS was used to assess soft tissue healing by primary intention following surgery at 1, 3, 7 and 14 days.
Results:
Results showed faster tissue healing when hyaluronic acid mixed with amino acids was used, and also a lower perception of pain by patients measured with a VAS scale.
Conclusions:
These data suggest the creation of larger research studies that can support the use of biologics for early soft tissue healing.
