Comparative study of cutaneous malignant melanoma according to anatomical site: plantar versus non-plantar melanoma
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View abstract on PubMed
Summary
This summary is machine-generated.Plantar melanomas, affecting the sole of the foot, exhibit more aggressive traits and poorer prognoses compared to melanomas elsewhere. This study highlights the plantar region as a significant poor prognostic indicator for melanoma patients.
Area Of Science
- Dermatology
- Oncology
- Pathology
Background
- Plantar melanomas present with more aggressive clinicopathological features.
- Higher mortality rates are observed in plantar melanomas compared to other sites.
Purpose Of The Study
- To compare clinicopathological features of plantar melanoma versus non-plantar melanoma.
- To identify prognostic factors differentiating plantar melanoma from melanomas at other anatomical locations.
Main Methods
- Retrospective comparative analysis of cutaneous melanoma patients over 20 years.
- Categorization into plantar melanoma and non-plantar melanoma groups.
- Inclusion of 239 patients (186 plantar, 53 non-plantar).
Main Results
- Plantar melanoma more prevalent in males and older individuals.
- Associated with greater Breslow depth, deeper Clark invasion, and higher ulceration rates.
- Increased incidence of lymphovascular and visceral metastases in plantar melanoma.
- Breslow thickness, distant metastasis, and traumatized areas linked to plantar melanoma prognosis.
Conclusions
- The plantar region is identified as a site associated with a poor prognosis for melanoma.
- Clinicopathological characteristics and prognostic factors differ significantly between plantar and non-plantar melanomas.
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