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Video laryngoscopy in neonate and infant intubation-a systematic review and meta-analysis
Ilari Kuitunen1,2, Kati Räsänen3,4, Tuomas T Huttunen5,6
1Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland. ilari.kuitunen@uef.fi.
Insights
Video laryngoscopy improves first attempt intubation success rates in neonates and infants. This method did not increase intubation time but reduced adverse events like desaturation and trauma.
Area of Science:
- Pediatric Anesthesiology
- Critical Care Medicine
Background:
- Video laryngoscopy has demonstrated improved first-pass intubation success and reduced intubation times in adults and older children.
- The efficacy of video laryngoscopy in neonates and infants requires further investigation.
Approach:
- A systematic review and meta-analysis was conducted.
- Included 13 studies involving neonates (age < 29 days) and infants (age < 365 days) requiring intubation.
- Assessed first attempt success rate, time to intubation, and adverse events using GRADE criteria.
Key Points:
- Video laryngoscopy use was associated with higher first attempt intubation success rates in both neonates (RR 1.18) and infants (RR 1.06).
- No significant difference in time to intubation was observed between video and direct laryngoscopy (MD 1.2s).
- Lower odds of desaturation (OR 0.62) and nasal/oral trauma (OR 0.24) were noted with video laryngoscopy.
Conclusions:
- Moderate certainty evidence suggests video laryngoscopy enhances first attempt intubation success in neonates and infants.
- Time to intubation remains comparable between video and direct laryngoscopy.
- Additional research is recommended to further optimize first intubation success rates in neonates.
Abstract:
We aimed to analyze the effect of video laryngoscopy on intubation success, time to intubation, and adverse events in infants and neonates. A systematic review and meta-analysis was performed, for which a neonates (age less than 29 days) and infants (age less than 365 days) needing to be intubated were included. The main outcomes were first attempt success rate in the intubation, time to intubation, and adverse events. Evidence certainty was assessed according to GRADE. We included 13 studies. Seven studies with 897 patients focused on neonates, and the first attempt success rate was higher in the video laryngoscopy group (RR 1.18, CI: 1.03-1.36). Six studies included 1039 infants, and the success rate was higher in the video laryngoscopy group (RR 1.06, CI: 1.00-1.20). Time to intubation was assessed in 11 trials, and there was no difference between the groups (mean difference 1.2 s, CI - 2.2 s to + 4.6 s). Odds of desaturation (OR 0.62, CI 0.42-0.93) and nasal/oral trauma (OR 0.24, CI 0.07-0.85) were lower in the video laryngoscopy group. Evidence certainties varied between moderate and low.
Conclusion:
We found moderate certainty evidence that the use of video laryngoscopy improves first attempt success rates in neonate and infant intubations, while the time to intubation did not differ between video and direct laryngoscopy groups. Further studies are still needed to improve the first intubation success rates in neonates.
What Is Known:
• Video laryngoscopy has been shown to improve first-pass intubation success rates and reduce time to intubation in adults and older children.
What Is New:
• Video laryngoscopy improved the first attempt intubation success rates both in neonates and in infants. • Video laryngoscopy did not increase the time to intubation, and it was associated with less adverse events than direct laryngoscopy.
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