Autologous transplantation of lung progenitor cells comes into reality for bronchiectasis
Jun-Qing Yue1, Rui-di Tang1, Wei-Jie Guan1
1Department of Allergy and Clinical Immunology, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, Guangzhou 510120, P.R. China; Guangzhou National Laboratory, Guangzhou, Guangdong 510005, P.R. China.
Abstract:
Stem and progenitor cell-based regenerative therapies have the potential to cure chronic respiratory diseases. Yan et al.1 reported a clinical trial of autologous P63+ progenitor cell transplantation in bronchiectasis patients, highlighting autologous transplantation of P63+ progenitor cells as a novel candidate therapeutic option to improve pulmonary gas exchange function and quality of life.
