Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Radioprotective agents derived from benzonitrile].

J P Fernandez, Y Robbe, J P Chapat

    Il Farmaco; Edizione Scientifica
    |January 1, 1986
    PubMed
    Summary

    Benzonitriles show potential as antiradiation agents. Specifically, 3,5-dinitrobenzonitrile demonstrated radioprotective activity with a dose modification factor (DRF) of 1.35 in mice.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Four-valve endocarditis caused by group G Streptoccocci.

    BMJ case reports·2025
    Same author

    Stratification of Metal and Sulphate Loads in Acid Mine Drainage Receiving Water Dams - Variables Regionalization by Cluster Analysis.

    Water environment research : a research publication of the Water Environment Federation·2015
    Same author

    Search for a two-Higgs-boson doublet using a simplified model in pp collisions at sqrt[s] = 1.96 TeV.

    Physical review letters·2014
    Same author

    Measurement of the bottom-strange meson mixing phase in the full CDF data set.

    Physical review letters·2012
    Same author

    Search for the standard model Higgs Boson produced in association with top quarks using the full CDF data set.

    Physical review letters·2012
    Same author

    Measurements of the top-quark mass and the tt cross section in the hadronic τ+jets decay channel at sqrt[s] = 1.96 TeV.

    Physical review letters·2012

    Area of Science:

    • Pharmacology
    • Radiochemistry

    Context:

    • Radioprotective agents are crucial for mitigating radiation damage.
    • Non-sulfur-containing compounds are being explored as alternatives to traditional radioprotectors.

    Purpose:

    • To evaluate benzonitriles as potential antiradiation agents.
    • To assess the radioprotective efficacy of 3,5-dinitrobenzonitrile.

    Summary:

    • Benzonitriles were investigated for their ability to protect against radiation.
    • 3,5-dinitrobenzonitrile exhibited significant radioprotective activity.
    • A dose modification factor (DRF) of 1.35 was consistently observed for 3,5-dinitrobenzonitrile.

    Impact:

    • Identifies benzonitriles, specifically 3,5-dinitrobenzonitrile, as promising non-sulfur radioprotective compounds.
    • Provides quantitative data (DRF) supporting the efficacy of this compound.
    • Suggests a new avenue for developing radiation protection strategies.

    Related Experiment Videos