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Exploring optical coherence tomography parameters in eyes with myopic tilted disc
Yu Qiao Zhang1, Xiu Juan Zhang1,2, Ru Yue Shen1,3
1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong SAR, China.
Eye and Vision (London, England)
|November 20, 2024
Summary
Optic disc torsion direction influences retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) thickness in myopic eyes. These factors are crucial for building accurate myopic normative databases.
Area of Science:
- Ophthalmology
- Optometry
- Retinal Imaging
Background:
- Myopic eyes exhibit unique optic disc morphology.
- Optic disc torsion (ODT), horizontal disc tilt (HDT), and ovality index (OI) are key morphological parameters.
- Understanding their impact on retinal layers is vital for ocular health assessment.
Purpose of the Study:
- To investigate the association between ODT, HDT angle, OI, and RNFL/GCIPL thickness in healthy myopic eyes.
- To determine if optic disc morphology influences specific retinal layer measurements.
- To provide insights for normative database construction in myopia.
Main Methods:
- Fundus photography was used to measure ODT and OI.
- Swept-source optical coherence tomography (SS-OCT) measured HDT angle, peripapillary RNFL, and macular GCIPL.
- Statistical analysis adjusted for age and axial length (AL).
Main Results:
- 335 eyes had temporal ODT and 195 had nasal ODT.
- Nasal ODT group: higher OI linked to thinner superior-to-superonasal GCIPL and temporal RNFL.
- Temporal ODT group: higher OI linked to thinner superior-to-nasal RNFL and thicker temporal RNFL.
- Larger HDT angle correlated with thinner superior-to-nasal RNFL and GCIPL.
Conclusions:
- Optic disc tortional direction significantly impacts RNFL and GCIPL measurements.
- These associations are independent of axial length and age.
- Optic disc morphology should be considered in myopic normative databases.
