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Author Spotlight: Exploring the Impact of Trauma on Cellular Aging
Published on: March 22, 2024
Telomeres: an organized string linking plants and mammals
Edison Di Pietro1, Romina Burla1,2, Mattia La Torre1
1Department of Biology and Biotechnologies "Charles Darwin", Sapienza, University of Rome, Rome, Italy.
None:
Telomeres are pivotal determinants of cell stemness, organismal aging, and lifespan. Herein, we examined similarities in telomeres of Arabidopsis thaliana, mice, and humans. We report the common traits, which include their composition in multimers of TTAGGG sequences and their protection by specialized proteins. Moreover, given the link between telomeres, on the one hand, and cell proliferation and stemness on the other, we discuss the counterintuitive convergence between plants and mammals in this regard, focusing on the impact of niches on cell stemness. Finally, we suggest that tackling the study of telomere function and cell stemness by taking into consideration both plants and mammals can aid in the understanding of interconnections and contribute to research focusing on aging and organismal lifespan determinants.
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