Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

128
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
128
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

134
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
134
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

160
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
160
Depression: Overview01:18

Depression: Overview

216
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
216
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

122
Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
122
Understanding Sleep01:11

Understanding Sleep

219
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
219

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low frequency blood-oxygen-level-dependent oscillations, <i>APOE4,</i> and plasma pTau<sub>217</sub>.

Journal of Alzheimer's disease : JAD·2026
Same author

Safety and Efficacy of Nerinetide at Year 1 in Participants Enrolled in ESCAPE-NEXT: A Multicenter, Double-Blind, Randomized Controlled Trial.

Journal of the American Heart Association·2026
Same author

Angiogenesis markers and cognitive response in a randomized trial of cognitive remediation plus transcranial direct current stimulation in older adults at risk of dementia.

Journal of Alzheimer's disease : JAD·2026
Same author

Predictors and Consequences of Serious Adverse Events in Patients Treated With Thrombolysis: A Prespecified Secondary Analysis of the AcT Trial.

Journal of the American Heart Association·2026
Same author

Biomarkers of angiogenesis in Alzheimer's disease: Systematic review and meta-analysis.

Journal of Alzheimer's disease : JAD·2026
Same author

Association of 24-Hour Computed Tomography Infarct Density on Functional Outcomes in Stroke: Secondary Analysis From the AcT Trial.

Journal of the American Heart Association·2026

Related Experiment Video

Updated: Jun 7, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

607

Depression, Obstructive Sleep Apnea and Cognitive Impairment (DOC) Screen Completion Time Reflects Executive

Sajeevan Sujanthan1, Alisia Southwell1, Tera Armel1

  • 1Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|November 21, 2024
PubMed
Summary

Screening completion time for depression, obstructive sleep apnea, and cognitive impairment (DOC) can predict cognitive deficits after stroke. Longer DOC screen times suggest potential issues with executive function and processing speed.

Keywords:
Cognitiondepressionexecutive functionsleep apneastroke

More Related Videos

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.3K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

698

Related Experiment Videos

Last Updated: Jun 7, 2025

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

607
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.3K
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD &#8212; A Safe, Cost-Effective Approach
04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

698

Area of Science:

  • Neurology
  • Neuropsychology
  • Gerontology

Background:

  • The depression, obstructive sleep apnea, and cognitive impairment (DOC) screen identifies post-stroke comorbidities.
  • Cognitive screening completion time is an underutilized outcome measure.

Purpose of the Study:

  • To determine if DOC screen completion time predicts cognitive impairment in patients at stroke/transient ischemic attack clinics.
  • To evaluate the utility of screening completion time as a novel outcome measure.

Main Methods:

  • 437 English-speaking patients at stroke prevention clinics underwent DOC screening and neuropsychological testing.
  • DOC screen scores and completion times were analyzed against the NINDS-CSC battery using multiple linear regression and ROC analysis.
  • Analyses controlled for age, sex, education, and stroke severity.

Main Results:

  • DOC screen completion time averaged 3.8 ± 1.3 minutes.
  • Longer completion times significantly predicted slower processing speed, reduced verbal fluency, and poorer executive function, but not memory.
  • Completion times exceeding 5.5 minutes indicated a high likelihood of executive and processing speed impairments.

Conclusions:

  • DOC screen completion time is a simple, feasible metric for routine clinical use.
  • Extended screening duration suggests deficits in executive functioning and processing speed, common yet challenging post-stroke impairments.
  • Screening time offers a valuable method for identifying under-recognized cognitive deficits following stroke.