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Updated: Jun 7, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Postoperative Opioid Reduction Using a Multimodal Pain Protocol for Outpatient Orthopaedic Sports Medicine Surgery
Ethan M Bernstein1, J Preston Van Buren2, Kieran S M Wolf2
1Department of Orthopaedic Surgery, US Naval Hospital Guam, Agana Heights, Guam, USA.
A new multimodal pain protocol in orthopaedic sports medicine significantly reduced opioid prescriptions by 43.6% without increasing patient pain scores. This approach effectively decreased long-term opioid use post-surgery.
Area of Science:
- Orthopaedic Surgery
- Pain Management
- Pharmacology
Background:
- Opioid medications are standard for postoperative pain in orthopaedic surgery.
- Multimodal pain management strategies can decrease opioid prescriptions in orthopaedic procedures.
Purpose of the Study:
- To assess the impact of a division-wide multimodal pain protocol on reducing opioid prescriptions and managing postoperative pain in orthopaedic sports medicine.
- To analyze opioid consumption and patient-reported pain levels following protocol implementation.
Main Methods:
- A retrospective cohort study compared pre- and post-protocol groups (n=40 each) for orthopaedic sports medicine procedures.
- Procedures were tiered based on pain levels, with a specific multimodal pain protocol applied to each tier.
- Outcomes measured included visual analog scale (VAS) pain scores at 2 weeks, opioid prescription quantities, and time to opioid discontinuation.
Main Results:
- Opioid prescriptions decreased by 43.6% post-protocol implementation (35.7 pills pre- vs. 20.1 pills post-protocol, P < .0001).
- No significant difference in VAS pain scores was observed at 2 weeks postoperatively (2.72 pre- vs. 2.99 post-protocol, P = .40).
- Continued opioid use at 2 weeks dropped significantly, with only 1 patient in the post-protocol group versus 20 in the pre-protocol group (P < .001).
Conclusions:
- Implementing a multimodal pain protocol in orthopaedic sports medicine effectively reduced opioid prescriptions without compromising 2-week postoperative pain control.
- Despite reduced prescriptions, 64.1% of prescribed opioids were consumed, suggesting potential for further optimization to prevent overprescription.
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