Related Experiment Video

Updated: Jun 7, 2025

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

8.8K

[Risk factors associated with myopic maculopathy in acquired myopia]

O V Kolenko1,2,3, L V Bushnina1, I E Pashentsev1

  • 1Khabarovsk branch of the S.N. Fedorov National Medical Research Centre "MNTK "Eye Microsurgery", Khabarovsk, Russia.

Vestnik Oftalmologii
|November 21, 2024
PubMed
Abstract

Insights

This study identified key factors contributing to myopic maculopathy (MM) in adults with acquired myopia. Corneal biomechanics, staphyloma characteristics, and choroidal thickness are strongly linked to MM development.

Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Engineering

Context:

  • Myopic maculopathy (MM) is a leading cause of vision impairment in individuals with high myopia.
  • Understanding the etiological factors of MM is crucial for developing effective prevention and treatment strategies.
  • Acquired myopia presents unique challenges in assessing MM risk factors compared to congenital myopia.

Purpose:

  • To identify and analyze the specific factors associated with the development of myopic maculopathy (MM) in patients diagnosed with acquired myopia.
  • To investigate the role of ocular structural and biomechanical properties in the pathogenesis of MM.
  • To establish a comprehensive risk profile for MM in a cohort of adult myopic patients.

Summary:

  • The study analyzed 135 patients with acquired myopia (age >30, axial length ≥26 mm), assessing MM presence using OCT-A and ultrasound.
  • Risk factors evaluated included age, axial length (AL), spherical equivalent (SE), staphyloma characteristics, choroidal and corneal thickness, and corneal biomechanics.
  • Significant associations with MM were found for age, AL, SE, extra-macular changes, staphyloma presence/size, choroidal thickness, corneal stromal thickness, and various corneal biomechanical parameters (DA, radius HC, PD).

Impact:

  • Identifies specific corneal biomechanical properties (e.g., corneal peak distance) and ocular structural metrics (staphyloma depth, nasal perifoveal choroidal thickness) as the strongest predictors of MM.
  • Provides valuable insights for ophthalmologists and optometrists in assessing MM risk and potentially guiding interventions.
  • Highlights the importance of a multi-faceted approach, considering both structural and biomechanical aspects of the eye in myopia management.
Keywords:
corneal thicknessmyopic maculopathyrisk factorsscleral staphyloma

More Related Videos

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.5K
Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways05:26

Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways

Published on: April 12, 2024

1.3K

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
508
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.7K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
2.5K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
393
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
437