Ketamine Versus Etomidate for Rapid Sequence Intubation: A Systematic Review and Meta-Analysis of Randomized Trials

Alisha Greer1,2, Mark Hewitt1,2, Parsa T Khazaneh2

  • 1Department of Medicine, Division of Emergency Medicine, McMaster University, Hamilton, ON, Canada.

Critical Care Medicine
|November 21, 2024
PubMed
Summary

Ketamine may increase hemodynamic instability but reduces vasopressor need and adrenal suppression compared to etomidate for emergent endotracheal intubation. The drugs show similar efficacy for first-attempt intubation and mortality outcomes.

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