Metoclopramide-induced tardive dyskinesia: a case report

Area of Science:

• Pharmacology
• Neurology
• Clinical Medicine

Background:

• Metoclopramide is a commonly prescribed medication.
• Neurological side effects, including tardive dyskinesia, can occur with metoclopramide use.
• Tardive dyskinesia is a serious adverse effect characterized by involuntary movements.

Purpose of the Study:

• To report a case of tardive dyskinesia associated with metoclopramide treatment.
• To review and present guidelines for the safe use of metoclopramide.
• To highlight the importance of physician awareness regarding metoclopramide's neurological side effects.

Main Methods:

• Case report presentation.
• Literature review on metoclopramide-induced side effects.
• Development of clinical guidelines for metoclopramide prescription.

Main Results:

• A patient developed tardive dyskinesia after 8 months of metoclopramide therapy.
• Acute extrapyramidal side effects are potential risks.
• Specific considerations for patients with renal insufficiency and the elderly are outlined.

Conclusions:

• Consultation-liaison psychiatrists must be aware of metoclopramide's neurological adverse effects.
• Adherence to established guidelines is crucial for minimizing risks associated with metoclopramide.
• Vigilance is necessary for early detection and management of metoclopramide-induced movement disorders.