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Updated: Jun 7, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Postoperative CSF Rhinorrhoea.

Aniruddha Bhagwat1, Chandrashekhar Deopujari1, Nishit Shah1

  • 1Bombay Hospital and Institute of Medical Sciences, Mumbai, India.

Acta Neurochirurgica. Supplement
|November 21, 2024
PubMed
Summary

Cerebrospinal fluid (CSF) rhinorrhoea, a complication of skull base surgery, requires precise leak identification for successful repair. Management strategies vary based on fistula location, surgical timing, and patient factors.

Keywords:
CSF rhinorrhoeaClivectomyEndoscopic endonasal skull base repairNasoseptal flap

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Area of Science:

  • Neurosurgery
  • Skull Base Surgery
  • Cerebrospinal Fluid Dynamics

Background:

  • Cerebrospinal fluid (CSF) rhinorrhoea is a recognized complication after skull base surgery.
  • Accurate identification of the CSF leak site is critical for effective management.

Purpose of the Study:

  • To highlight the challenges in recognizing and managing postoperative CSF rhinorrhoea.
  • To present strategies for successful surgical repair of CSF fistulas.

Main Methods:

  • Case study analysis of two patients with postoperative CSF rhinorrhoea.
  • Discussion of transcranial and transnasal surgical approaches.

Main Results:

  • Successful repair depends on accurate fistula localization, surgical timing, and patient-specific factors.
  • Illustrative cases demonstrate neurosurgical challenges in CSF leak management.

Conclusions:

  • Prompt and accurate diagnosis of CSF leak is essential for timely intervention.
  • Tailored surgical approaches, considering fistula site and patient factors, are key to successful CSF rhinorrhoea repair.