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Updated: Jun 7, 2025

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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Published on: November 26, 2018
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Inflammatory Waldenström macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort
Pierre-Edouard Debureaux1,2,3, Stéphanie Poulain4, Stéphanie Harel3
1Institut de Recherche Saint-Louis, University Paris Cité, INSERM U1160, Paris, France.
Blood
|November 21, 2024
Abstract:
Inflammatory form of Waldenström macroglobulinemia (iWM) predicts outcomes after immuno-chemotherapy and Bruton tyrosine kinase inhibitors, but its origin is unknown. Here, we unravel increased clonal hematopoiesis in patients with iWM (61% vs 23% in noninflammatory WM), suggesting a contribution of environmental cells to iWM.
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