The impact of overseas assignments on metabolic factors: Panasonic cohort study 23
Tetsuya Murano1, Hiroshi Okada2, Masahide Hamaguchi2
1Department of Health Care Center, Panasonic Health Insurance Organization, 5-55 Sotojima-cho, Moriguchi 570-8540, Japan.
Objectives:
This study aimed to assess the effects of overseas assignments on the metabolic factors associated with lifestyle disease including body mass index, blood pressure, plasma glucose, lipid profiles, liver enzyme, and uric acid in Japanese individuals.
Methods:
A retrospective cohort study was conducted using annual health examination data from employees of the Panasonic Corporation in Japan. We evaluated the differences in the changes in metabolic factors associated with lifestyle disease during the observation periods between the overseas and non-overseas assignment groups. Propensity score matching was performed to match the characteristics of the two groups. In subgroup analysis, the impact of family accompaniment and the destination on metabolic factors associated with lifestyle disease were also evaluated.
Results:
The median ages of the overseas (n = 899) and non-overseas assignment groups (n = 899) were 46 (41-50) and 46 (41-50) years. The average overseas assignment duration was 4.1 ± 1.7 years. Overall, 65.4% of individuals were assigned overseas alone in the overseas assignment group. No significant differences were observed in the changes in metabolic factors associated with lifestyle disease between the overseas and non-overseas assignment groups. In subgroup analyses, the family accompaniment and the destination did not affect changes in any of metabolic factors associated with lifestyle disease during the overseas assignment.
Conclusions:
In conclusion, no significant difference was observed in metabolic factors associated with lifestyle disease between the overseas and non-overseas assignment groups in Japanese employees.
More Related Videos
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
02:55Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
Published on: October 6, 2023
Related Concept Videos
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Factors Affecting Drug Biotransformation: Biological
Species differences: Variations in enzyme systems across species can cause disparities in drug metabolism. For instance, humans may metabolize certain drugs faster than rodents, altering therapeutic effects.
Strain differences: Genetic variations within a species can result in differing enzyme activity, impacting drug response and toxicity. For example, some mouse strains may...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
