Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

1.8K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
1.8K
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

436
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
436

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Different temporal dynamics of foveal and peripheral visual processing during fixation.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Tapping on a target: dealing with uncertainty about its position and motion.

Experimental brain research·2022
Same author

Pursuing a target with one's eyes helps judge its velocity.

Perception·2022
Same author

Scene variability biases our decisions, but not our perceptual estimates.

Journal of experimental psychology. Human perception and performance·2022
Same author

StimuliApp: Psychophysical tests on mobile devices.

Behavior research methods·2020
Same author

Decoupling sensory from decisional choice biases in perceptual decision making.

eLife·2019

Related Experiment Video

Updated: Jan 6, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

4.3K

A Systematic Review and Meta-Analysis on Contrast Sensitivity in Schizophrenia.

Daniel Linares1,2, Aster Joostens1, Cristina de la Malla1,2

  • 1Vision and Control of Action Group, Departament de Cognició, Desenvolupament i Psicologia de l'Educació, Facultat de Psicologia, Universitat de Barcelona, 08035 Barcelona, Spain.

Schizophrenia Bulletin
|November 22, 2024
PubMed
Summary

Individuals with schizophrenia exhibit reduced contrast sensitivity, a key visual function measure. Further research is needed to understand the impact of medication and attentional lapses on this visual deficit.

Keywords:
contrastlapsesmedicationmeta-analysisreviewschizophreniasensitivity

More Related Videos

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.6K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.0K

Related Experiment Videos

Last Updated: Jan 6, 2026

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
05:14

Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

Published on: September 8, 2021

4.3K
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.6K
Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

19.0K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Visual Perception

Background:

  • Perceptual alterations in mental disorders offer insights into neural and computational anomalies.
  • Schizophrenia is associated with various visual feature deficits, including contrast sensitivity.
  • Existing evidence for contrast sensitivity deficits in schizophrenia requires comprehensive synthesis.

Purpose of the Study:

  • To systematically review and meta-analyze studies on contrast sensitivity in schizophrenia.
  • To synthesize the evidence for contrast sensitivity deficits in individuals with schizophrenia.
  • To identify factors influencing contrast sensitivity in schizophrenia.

Main Methods:

  • Systematic review and meta-analysis of published studies.
  • Inclusion of studies measuring contrast sensitivity in schizophrenia patients and healthy controls.
  • Analysis of 46 identified studies, with a focus on 43 studies involving chronic schizophrenia patients.

Main Results:

  • A significant reduction in contrast sensitivity was observed in patients with chronic schizophrenia (g = 0.74, P < 10-9).
  • Medication emerged as a potential confounding factor influencing the observed deficit.
  • Attentional lapses and visual acuity were not adequately assessed, limiting understanding of their contribution.

Conclusions:

  • A robust contrast sensitivity deficit is confirmed in chronic schizophrenia.
  • The roles of medication and attentional lapses in this deficit require further investigation.
  • Future research should address these factors to elucidate the underlying mechanisms.