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Updated: Jun 6, 2025

Screening Assay for Oxidative Stress in a Feline Astrocyte Cell Line, G355-5
Published on: July 13, 2011
[Oxidative stress in the pathogenesis of chronic headache]
1Pirogov Russian National Research Medical University, Moscow, Russia.
Abstract:
Given new information about the development of oxidative stress (OS) in chronic headache. The main biochemical characteristics of OS are presented. Changes in MRI and biochemical markers confirming the development of OS in migraine are described. The absence of significant differences in OS rates for migraine without aura and with aura is emphasized. The pathophysiological differences between migraine and chronic tension headache, in which OS is not detected, are shown. The possible activation of TRPA1 ion channels and CGRP peptides during OS, which provokes migraine attacks, is discussed. Directions of pathogenetic therapy OS are given.
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