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Updated: Jun 6, 2025

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
[The follow-up examination of children with breath-holding spells]
1Belgorod Children's Regional Hospital, Belgorod, Russia.
Insights
Breath-holding spells in children may predict future autonomic dysfunction, sleep disturbances, and anxiety disorders. This study followed 72 children to analyze developmental features and health conditions.
Area of Science:
- Pediatrics
- Developmental Psychology
- Neurology
Objective:
The follow-up study of the developmental features of children suffering from breath-holding spells.
Material And Methods:
Seventy-two primary school age children suffering from the breath-holding spells were examined. Somatic, neurological and autonomic status has been followed-up and children developmental features have been analyzed. The Achenbach System of Empirically Based Assessment (ASEBA) for children of 6-18 years old, Zakharov and Lavrentieva-Titarenko anxiety tests were used in the work in addition to clinical research methods.
Results:
According to the data obtained, 47.2% of children with a history of breath-holding spells suffer from conditions such as somatoform dysfunction of the gastrointestinal tract, tension headache, vegetative and vascular dystonia, dissomnia, emotional lability syndrome.
Conclusion:
The presence of breath-holding spells in children can be considered as a predictor of the autonomic dysfunction development, sleep disorders and anxiety disorders in future.
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