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Updated: Jun 6, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Different types of combined endoscopic and transcranial approaches for complex giant pituitary adenomas: how I do it
Ao Shen1, Dongjie Zhou1, Yue Min2
1Department of Neurosurgery, West China Hospital/West China School of Medicine, Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan, China, 610041.
Background:
Surgery for giant pituitary adenomas (GPAs) poses significant challenges, particularly when the tumor cannot be fully addressed using either the endoscopic endonasal approach (EEA) or the microscopic transcranial approach (MTCA) alone.
Method:
We utilized two combined approaches for complex GPAs: 1) expanded endoscopic endonasal approach (EEEA) combined with microscopic pterional approach (MPA), and 2) EEEA combined with endoscopic transventricular approach (ETVA).
Conclusion:
The combined approach is an effective surgical technique for complex GPAs. The EEEA-MPA approach is suitable for GPAs with superior and lateral extension, while the EEEA-ETVA approach is beneficial for tumors with lateral ventricular invasion.

