Evidence-Based Guidelines for Keratorefractive Lenticule Extraction Surgery.
Yan Wang1, Lixin Xie2, Ke Yao3
1Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Tianjin, China; Nankai University Eye Institute, Nankai University, Tianjin, China; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.
Ophthalmology
|November 22, 2024
Summary
New guidelines offer evidence-based recommendations for keratorefractive lenticule extraction (KLEx) procedures. These guidelines aim to improve patient outcomes and minimize complications in refractive surgery.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Corneal Surgery
Background:
- Keratorefractive lenticule extraction (KLEx) involves removing corneal tissue via small incisions, avoiding flaps.
- KLEx has rapidly gained popularity for refractive correction.
- No established clinical practice guidelines previously existed for KLEx.
Purpose of the Study:
- To develop evidence-based clinical practice guidelines for keratorefractive lenticule extraction (KLEx).
Main Methods:
- Guidelines developed using WHO methodology, AGREE II, and PRIME statement.
- Evidence synthesized from 8 literature databases and 5 guideline databases.
- Recommendations formulated via Delphi consensus of 44 global experts.
Main Results:
- 38 recommendations developed for KLEx, covering screening, planning, surgery, and complications.
- 29 (76%) recommendations were strong, focusing on effective refractive correction and complication management.
- Corneal biomechanics and research gaps for enhancing safety were identified.
Conclusions:
- Evidence-based guidelines for KLEx are now available for clinical practice.
- Guidelines address preoperative screening, surgical planning, and complication management.
- Implementation is expected to minimize complications and enhance outcomes in refractive surgery.
