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Updated: Jun 6, 2025

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
Weapon of choice: viruses share cross-kingdom tools
1Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Abstract:
Following on from the discovery that innate immune pathways are shared widely across the tree of life comes another surprise: Hobbs et al. show that viruses targeting animals and bacteria also use highly conserved tools to fight back. Why such mechanisms remain seemingly unchanged despite the rapid coevolution among hosts and pathogens is now a key open question for the field.
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