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Updated: Jun 6, 2025

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

Published on: December 19, 2016

Quantitative Sensory Testing - From bench to bedside.

Sam Hughes¹, Jan Vollert¹, Roy Freeman²

¹Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.

International Review of Neurobiology

|November 23, 2024

Summary

This summary is machine-generated.

Quantitative Sensory Testing (QST) evaluates the somatosensory nervous system. This overview covers laboratory, bedside, and dynamic QST methods, discussing their pros and cons for assessing nervous system function and improving patient care.

Keywords:

Bedside QST Bedside testing Dynamic QST Lab QST Pain QST Quantitative sensory testing Sensory perception Sensory phenotyping Sensory testing

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Area of Science:

Neuroscience
Psychophysics
Clinical Assessment

Background:

Quantitative Sensory Testing (QST) uses standardized procedures to assess somatosensory nervous system integrity.
Various QST protocols exist, aiming to identify sensory function changes for better patient care.
Laboratory QST is the gold standard but is resource-intensive; simpler bedside and dynamic QST methods have been developed.

Purpose of the Study:

To provide a comprehensive overview of Quantitative Sensory Testing (QST) methodologies.
To compare and contrast laboratory, bedside, and dynamic QST approaches.
To discuss the advantages and limitations of each QST modality.

Main Methods:

Review of established laboratory-based QST protocols.
Description of simplified bedside QST protocols for clinical settings.
Explanation of dynamic QST methods, including conditioned pain modulation (CPM).

Main Results:

Laboratory QST offers high standardization but requires trained personnel and equipment.
Bedside QST protocols are designed for ease of implementation and cost-effectiveness.
Dynamic QST assesses functional pain responses, often building upon static assessments.

Conclusions:

QST methodologies, including lab, bedside, and dynamic approaches, are crucial for understanding somatosensory function.
Each QST type has unique benefits and drawbacks impacting clinical application and research.
Standardized QST assessments are vital for accurate diagnosis and improved patient management.